Jose Santiago
- Given Name
- Jose Rafael
- Nickname(s)
- Palillo
- Born
- 8/15/1940 — Juana Diaz, P.R.
- Weight
- 185 lbs
- Height
- 6' 2"
- Throws
- R
- Bats
- R
- Team(s)
- Kansas City Athletics (1963–1965)Boston Red Sox (1966–1970)
- Debut
- 1963-09-09
- Final Game
- 1970-07-06